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Osteoclast formation

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Q&A: How are osteoclasts formed?

Author: Sanketh DS, MDS

Osteoclasts are large multinucleated giant cells having a few dozen nuclei, whose function is to resorb bone. They play a very important role in bone remodelling and are characterized by the presence of an enzyme called tartrate resistant acid phosphatase(TRAP). Osteoclasts are haematopoietic in origin and are derived from the monocyte/macrophage lineage of cells.

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