Author: Sanketh DS, MDS
Amelogenesis is the process of enamel formation, which starts with deposition of enamel matrix by ameloblasts, followed by mineralization of the matrix. Enamel matrix essentially consists of organic material composed of two groups of proteins, namely amelogenins and non-amelogeins. Non-amelogenins consist of proteins enamelin, tuftelin and ameloblastin. The amelogenins form bulk of the enamel proteins, comprising at least 90%. Once enamel is fully formed, organic material makes up 4% of enamel. The inorganic portion of enamel is composed of hydroxyapatite and comprises 96% of enamel.
Amelogenesis is divided into 3 stages referred to as pre-secretory, secretory and maturation stages.
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