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Central giant cell granuloma



CENTRAL GIANT CELL GRANULOMA: PATHOGENESIS, CLINICAL FEATURES, HISTOPATHOLOGY & TREATMENT

Author: Sanketh DS, MDS

INTRODUCTION

Central giant cell granuloma (CGCG), first described by Jaffe in 1953 is a benign intra-osseous lesion characterised by the presence of giant cells histologically. Jaffe described it as a reactive and reparative granulation tissue reaction occurring in the bones as a result of trauma and did not consider it to be a true neoplasm. He called them “giant cell reparative granuloma”.

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