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Oral lichen planus – Pathogenesis



ORAL LICHEN PLANUS – AUTOIMMUNE PATHOGENESIS

Author: Sanketh DS, MDS

AUTOIMMUNE PATHOGENESIS

Essentially, the body’s own immune cells (lymphocytes) attack the oral mucosal cells (keratinocytes) to cause oral lichen planus. An early event in the causation of the lesion, is the unmasking of the keratinocyte antigen. This unmasking could be induced by numerous factors like stress, drugs, bacterial or viral infections and other unknown agents. 

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