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Pemphigus vulgaris

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PEMPHIGUS VULGARIS: CLINICAL FEATURES,HISTOLOGY & TREATMENT

Author: Sanketh DS, MDS

INTRODUCTION

Pemphigus vulgaris is an autoimmune muco-cutaneous condition occurring as a result of inappropriate production of auto-antibodies against desmosomes holding the epithelial cells together, leading to an intra-epithelial blister formation. There is widespread ulceration of the skin, oral mucosal and other mucosal surfaces causing much pain and debilitation.

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