ORAL SUBMUCOUS FIBROSIS: PATHOGENESIS, CLINICAL FEATURES, HISTOPATHOLOGY AND TREATMENT
Author: Sanketh DS, MDS
Oral submucous fibrosis (OSF), first described by Schwartz in 1952, is a chronic, progressive, scarring disease due to an altered collagen metabolism that is classified as a potentially malignant disorder. It is characterised by dense fibrosis of the submucosal tissues of the oral cavity making it difficult to swallow and open the mouth. It predominantly affects people of the Indian sub-continent, China and other countries in South East Asia.
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