WARTHIN’S TUMOR: CLINICAL FEATURES, HISTOPATHOLOGY & TREATMENT
Author: Sanketh DS, MDS
Warthin’s tumor also known as papillary cystadenoma lymphamatosum (PCL) is the 2nd most common benign salivary gland tumor, first described by Warthin in 1929. This lesion has an almost restricted occurrence for the parotid gland, comprising 5-22% of all parotid neoplasms, although it may very rarely occur in the submandibular glands or other minor salivary glands. Though Warthin’s tumor is believed to be a benign tumor, there are studies which suggest that this lesion may not be a true neoplasm.
ETIOLOGY AND PATHOGENESIS
Although the pathogenesis of this lesion is unknown, there are a few theories that have been put forth. The commonly accepted hypothesis suggests that heterotopic salivary gland tissue proliferate within intra-parotid or para-parotid lymph nodes to give rise to the lesion.
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